Cancer stem cells: new therapeutic strategies for metastatic colon cancer
Nature - It has been demonstrated that cancer stem cells (CSCs) play a major role in promoting tumor progression and metastasis. A study conducted by a team of American researchers analyzed the distinct roles played by CSCs in the growth of primary and metastatic tumors. The results of this study suggest that eliminating CSCs may be a therapeutic strategy for managing metastatic cancer.
Cancer stem cells: new therapeutic strategies for metastatic colon cancer
"A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer"
Authors: Felipe de Sousa e Melo, Antonina V. Kurtova, Jonathan M. Harnoss, Noelyn Kljavin, Joerg D. Hoeck, Jeffrey Hung, Jeffrey Eastham Anderson, Elaine E. Storm, Zora Modrusan, Hartmut Koeppen, Gerrit J. P. Dijkgraaf, Robert Piskol & Frederic J. de Sauvage
Nature - doi:10.1038/nature21713 - 29 March 2017
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"Cancer: Tumour stem-cell surprises"
Author: Florian R. Greten
Nature - doi:10.1038/543626a - 29 March 2017
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